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Oct 22,  · Generally, Cialis is a safe drug. However, you need to consider the other substances you take with it and the effects the combination can cause. For example, alcohol and Cialis may digitales.com.au: James Roland. Tadalafil (10 mg or 20 mg) did not affect alcohol plasma concentrations and alcohol did not affect tadalafil plasma concentrations. · Notes for Consumers: Grapefruit juice and grapefruit-containing foods may increase the side effects of Tadalafil (Cialis). Do not significantly alter grapefruit juice intake while taking this drug, or avoid grapefruit juice if digitales.com.auted Reading Time: 3 mins. Dec 11,  · Although most drugs for ED work in similar ways, studies have found that ED drugs have different levels of risk when paired with alcohol. Since people who take Cialis sometimes get low blood pressure when they drink, the Food and Drug Administration (FDA) has put a warning on Cialis for use with digitales.com.auted Reading Time: 5 mins. Read More...

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