Adult vs embryonic stem cells - excellent message
Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Retrovirology , 19 Apr , 3: 24 DOI: Many novel studies and therapies are possible with the use of human embryonic stem cells hES cells and their differentiated cell progeny. The hES cell derived CD34 hematopoietic stem cells can be potentially used for many gene therapy applications. Here we evaluated the capacity of hES cell derived CD34 cells to give rise to normal macrophages as a first step towards using these cells in viral infection studies and in developing novel stem cell based gene therapy strategies for AIDS. Undifferentiated normal and lentiviral vector transduced hES cells were cultured on S17 mouse bone marrow stromal cell layers to derive CD34 hematopoietic progenitor cells. The differentiated CD34 cells isolated from cystic bodies were further cultured in cytokine media to derive macrophages.Adult vs embryonic stem cells Video
Debate Over Embryonic Stem Cell Research (vs Adult Stem Cells) adult vs embryonic stem cellsFor: Adult vs embryonic stem cells
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The key difference between adult and embryonic stem cells is that adult stem cells are multipotent while embryonic stem cells are pluripotent. Stem cells are a category of cells with the ability to divide and develop into different types of cells in the body.
They are distinguished from the normal cells since they divide and renew themselves over a longer period of time. Moreover, they are unspecialized cells with no specific cellular function in the body. They have the potential to differentiate and become specialized cells in the body such as brain cells, blood cells, and muscle cells. Adult stem cells and embryonic stem cells are two types of stem cells. Overview and Key Difference 2.
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What are Adult Stem Cells 3. What are Embryonic Stem Cells 4. Adult stem cells are present in differentiated tissues of the body.
These tissues include skeletal muscle, liver, pancreas, brain, eye, dental pulp, skin, bone marrow, blood and lining of the gastrointestinal tract. Moreover, adult stem cells remain in these tissues undifferentiated, with continuous self-renewal and producing identical copies of cells throughout the lifetime of the organism.
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They undergo differentiation into specialized cells of their tissues of origin when needed. Hematopoietic stem cells are a type of adult stem cells present in the bone marrow. They are considered multipotent stem cells as they give rise to different types of blood cells from a single type of cells. Regulated gene expression is responsible for these variations in differentiated cells. It is controlled by special types of transcription factors. Also, stem cells present in the brain are multipotent.
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They give rise to both muscle and blood cells. Embryonic stem cells are the undifferentiated cells present in the inner cell mass of the blastocyst — a hollow ball of cells developed from the zygote after rapid mitosis. Hence, these stem cells are categorized as stem cells present in the early stages of embryonic development. Embryonic stem cells are pluripotent.]
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