What stage of the demographic transition is mexico in - digitales.com.au

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The Demographic Transition Model (DTM)

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With a population of about million in , [1] Mexico is the 10th most populated country in the world. It is the most populous Spanish-speaking country and the third-most populous in the Americas after the United States and Brazil. The most populous city in the country is the capital, Mexico City , with a population of 8. In total, about The National Commission for the Development of Indigenous Peoples CDI , also undertakes research and analysis of the sociodemographic and linguistic indicators of the indigenous peoples. In , the Mexican population was

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There has been limited study of Native American whole genome diversity to date, which impairs effective implementation of personalized medicine and a detailed description of its demographic history. On average, each individual has 3. By detecting signals of positive selection we report 24 enriched key pathways under selection, most of them satge to immune mechanisms. Population genomics and phylogenetic analyses demonstrated stratification in a Northern-Central-Southern axis, with major substructure in the Central region. The Seri, a northern group with the most genetic divergence in our study, showed a distinctive genomic context with the most novel variants, and the most population specific genotypes. Genome-wide analysis showed that the average haplotype blocks are longer in Native Mexicans than in other world populations.

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With this dataset we describe previously undetected population level variation in Native Mexicans, helping to reduce the gap in genomic data representation of such groups. This is an open access article distributed link the terms of the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The datasets included are in VCF format, and cover every variant found, with the corresponding allele frequency in our studied population; it also includes spreadsheet for subsets of interest for easy exploration.

what stage of the demographic transition is mexico in

In alignment with the respective Institutional Review Board transiiton and individual informed consents, any other BAM or VCF file will be available upon request to avoid compromising the participant's privacy. Please direct requests to Prof. Funding: Winter Genomics provided support in the form of salaries for author FPV, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The author s received no other specific funding for this work.

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The study of the biology and evolutionary history of our species, as well as effective implementation of genomic medicine, require a broad understanding of the human genomic variation across the world. While some genomic variation is shared by populations from all continents, which is described as common or ancient variation, other polymorphisms of more recent origin are limited to specific regions, which are responsible for population specific phenotypic traits and health risks [ 12 ].

Native Americans NatAm have been through a deep and rapid population transition in the recent history of our species.

what stage of the demographic transition is mexico in

Most of the highly diverse contemporary NatAm populations descend from a small group of inhabitants of Siberia [ 3 ] and some other streams of ancestral groups [ 4 — 7 ]. Once the last glaciation ended, about 15, years ago, ancient NatAm readily moved along the whole continent and populated a wide array of ecosystems [ 8 ], ranging from coastal areas, to deserts, mountain ranges and tropical forests.]

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