Opinion: Reproductive system articles
| JAMES TAYLOR WEST WING | 9 hours ago · (LifeSiteNews) – Thousands of women around the world are reporting disrupted menstrual cycles after receiving injections of COVID vaccines. The U.K.’s government vaccine adverse event system has collected more 2, reports of reproductive disorders after coronavirus injections, including excessive or absent menstrual bleeding, delayed menstruation, vaginal hemorrhaging, . 1 day ago · Background Most orchid species have been shown to be severely pollination limited, and the factors affecting reproductive success have been widely studied. However, the factors determining the reproductive success vary from species to species. Habenaria species typically produce nectar but exhibit variable fruit set and reproductive success among species. Here, we investigated the . 1 day ago · The Rhesus (Rh) blood group system is the next most clinically significant blood group system following the ABO blood group. Rh D-negative women are at risk of alloimmunization following exposure to Rh D-positive blood. The exposure of Rh D-negative women to Rh D-positive fetal blood may cause hemolytic disease of the fetus or new-born due to Rh incompatibility. |
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Reproductive system articles Video
Grade 5- THE MALE REPRODUCTIVE SYSTEM - Science 5Reproductive system articles - something is
Origin[ edit ] The term reproductive justice combines reproductive rights and social justice. It was coined and formulated as an organizing framework by a group of Black women who came together for that purpose in and called themselves Women of African Descent for Reproductive Justice. Foundation for Women with the intention of creating a statement in response the Clinton administration's proposed plan for universal health care. The conference was intentionally planned just before the attendees would be going to the International Conference on Population and Development in Cairo, which reached the decision that the individual right to plan one's own family must be central to global development. The women developed the term as a combination of reproductive rights and social justice, and dubbed themselves Women of African Descent for Reproductive Justice. Willis, and Kim Youngblood. These women felt that despite having the legal access to options such as abortion, they were not able to exercise reproductive choices as easily as their more privileged counterparts.Each of these organs presents with a unique course of biological development as well as of malignant degeneration. For many decades, various preclinical in vitro models have been employed artifles study female reproductive organ patho- biology, however, facing important shortcomings of limited expandability, loss of representativeness and inadequate translatability to the clinic.
The recent emergence of 3D organoid models has propelled the field forward by generating powerful research tools that in vitro replicate healthy as well as diseased human tissues and are amenable to state-of-the-art experimental interventions. Here, we in detail review organoid reproductie of the different female reproductive organs from healthy and tumorigenic backgrounds, and project perspectives for both scientists and clinicians.
Introduction The female reproductive system serves a unique purpose as it harbors the beginning of reproductive system articles, but, conversely, also risks to bring about the very end of it. The embryonic etiology of these closely related tissues are threefold Brauer, ; Mutter and Robboy, The vulva and lower third of the vagina arise from ectoderm.
Review ARTICLE
The tissues making up the actual female reproductive tract FRTincluding upper two-thirds of the vagina, cervix, uterus, endometrium and fallopian tubes FTreproductive system articles mesodermal derivatives whereas the ovaries originate read more the endoderm. Each of these tissues is epitomized by its unique patterns of development, proliferation and differentiation.
Importantly, to serve their reproductive purpose, these tissues rely on the self-renewing capacity of their define gatorade Patterson and Pru, However, it is in their efforts that allow for life to begin, repgoductive fulfilling transportation functions, supporting implantation and serving as barriers reproductive system articles internal and external stressors and pathogens, that its constituents risk cellular deregulation due to threatening impacts such as hormonal dysregulation, infections or auto-immune diseases, which may ultimately result in carcinogenesis Hanahan and Weinberg, ; Reproductivr, In general, insight in tissue development, homeostasis and disease has been obtained from several research models that throughout the years have become more complex and representative, and even personalized Schutgens and Clevers, For many years, hypothesis testing for tissues of the FRT has relied on two-dimensional 2D models such as cell lines that have stood alongside short-term three-dimensional 3D in vitro cell-culture such as spheroids and in vivo explant systems [such as patient-derived xenografts PDXs ] Adissu et al.
It took untilhowever, for the prospect of a complete transition into use of long-term 3D in vitro cell-culturing methods to be envisioned. The insights brought about by this novel technology, reliant reproductive system articles the use of a gel-based substitute for the local extracellular matrix ECM and supplementation of feeder- and serum-free stem cell niche-supporting factors, were manifold Kleinman et al. This system was the first to show defined use of growth and regulatory factors required by the stem articcles niche, thereby discarding the need for highly variable and ill-defined serum supplements Clevers et al. Contrary to 2D cell lines, organoids proved to remain reproductive system articles, genomically and transcriptomically stable over a long period of time and serial passaging. This novel culturing method thereby allowed for spatiotemporal tracking i.
Rapidly and effectively, the complex biology of the epithelial syste of the intestine was analyzed for the entire spectrum spanning healthy to diseased conditions Sato et al. Overall, more reliably than other experimental models, organoids enable a wide variety of basic, translational and clinical research prospects such as deciphering the heterogeneous make-up of tissues via multi-omic analyses, unraveling host tissue-pathogen interactions, and advancing precision and regenerative medicine using cryopreserved and biobanked organoid lines Figure 2. Organoids are also amenable to cutting-edge reproductive system articles technologies such as CRISPR-Cas9 gene editing, and can be efficiently subjected to live imaging Kim et al.
Research models for the female reproductive tract.
INTRODUCTION
Applications of organoid model systems. Organoids are stable 3D in vitro representations of the reproductive system articles of origin that adequately recapitulate tissue patho- biology, and are amenable to manifold basic and pre- clinical research applications reproductive system articles as multi-omic scrutiny and gene-editing, host—pathogen interaction mapping and regenerative medicine, biobanking and high-throughput drug testing toward patient-tailored treatments. In this review, we aim to systematically list the efforts made in the field of organoid research for the tissues that make up the human FRT. We provide a systematic overview of the organoid models developed and the growth media that detail the niche requirements ranging from healthy to diseased states. We critically appraise their validity and scrutinize reports for investigated applications. Taken together, we aim to highlight the specific benefits of organoid technology in the setting of desired and unwelcome processes of the human FRT.
Vulva The vulva, that visit web page of labia majora, mons pubis, labia minora, clitoris and vestibulum, acts as a gatekeeping structure and serves as a first line of defense in order to protect the FRT against extracorporeal stressors.]
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