In postmarketing experience, jaundice and hepatic enzyme elevations mostly consistent with cholestasis or hepatitisin some cases severe enough to require hospitalization, have been reported in association with use of amlodipine. Amlodipine has been used safely in patients with chronic obstructive pulmonary disease, well-compensated congestive heart failure, coronary artery disease, peripheral vascular disease, diabetes mellitus, and abnormal lipid profiles. Sometimes, learn more here will prescribe a medicine for a condition that is not written in the patient information leaflets.
Proper Use
Angina is a pain or discomfort that keeps coming back when part of your heart does not get enough blood. For most people, amlodipine keeps lowering the blood pressure for 24 hours or longer.
Talk to your doctor about the best time of day to take your blood pressure when is it best to take amlodipine besylate. Co-administration of amlodipine visit web page digoxin did not change serum digoxin levels or digoxin renal clearance in normal volunteers. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
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Ans: Yes, it might cause itching in some patients, though it is a rare side effect. Keep amlodipine besylate tablets away from children. Co-administration of multiple 10 mg doses of amlodipine with 80 mg of atorvastatin resulted in no significant change in the steady-state pharmacokinetic parameters of atorvastatin. Read this information carefully before you start taking amlodipine besylate tablets and each time you refill your prescription.
1.2 Coronary Artery Disease (CAD)
Only use amlodipine besylate tablets the way your doctor told you to. A similar increase in AUC was observed in patients with moderate to severe heart failure. Carcinogenesis, Mutagenesis, Impairment of Fertility Rats and mice treated with amlodipine maleate in the diet for up to two years, at concentrations calculated to provide daily dosage levels of 0. When is it best to take amlodipine besylate studies of bst did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
Antihypertensive therapy: nocturnal dippers and nondippers. Differential effects of morning or evening dosing of amlodipine on circadian blood pressure and heart rate. Drug Label Info. Amlodipine besylate tablet, USP is indicated for the symptomatic treatment of chronic stable angina.
Call your doctor for medical advice about side effects. The antihypertensive efficacy of amlodipine besylate when is it best to take amlodipine besylate been demonstrated in a total of 15 double-blind, placebo-controlled, randomized studies involving patients on amlodipine and on placebo. If click at this page took too much amlodipine besylate tablets, call your doctor or Poison Control Center, or go to the nearest hospital emergency room right away.
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NDC 1 2 3 4 5 6 This inhibition of coronary spasm is responsible for the effectiveness of amlodipine in vasospastic Prinzmetal's or variant angina. Psychiatric: sexual dysfunction male 1 and femaleinsomnia, nervousness, depression, abnormal dreams, anxiety, depersonalization. In vitro data indicate that amlodipine has no effect on the human plasma protein binding of digoxin, phenytoin, warfarin, and indomethacin. Simvastatin Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. |
Amlodipine besylate is a white or almost white powder with a molecular weight of Although the study did not show significance on the primary objective of change in coronary luminal diameter as assessed by quantitative coronary angiography, the data suggested a favorable outcome with respect to fewer hospitalizations for angina and revascularization procedures in patients with CAD.
A total of Only use amlodipine besylate tablets the way your doctor told you to.
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In clinical studies in which amlodipine was administered in combination with beta-blockers to patients with either hypertension or angina, no adverse effects on electrocardiographic parameters were observed. Limit the dose of simvastatin in patient on amlodipine to 20 when is it best to take amlodipine besylate daily 7. Tell your doctor if you:.
Was this content helpful? Effects were similar in black patients and in white patients. Amlodipine besylate tablet, USP may be used as monotherapy or in combination with other antianginal agents.