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What is the generic name for clopidogrel bisulfate

what is the generic name for clopidogrel bisulfate

Mar 01,  · The empirical formula of clopidogrel bisulfate is C 16 H 16 ClNO 2 S•H 2 SO 4 and its molecular weight is The structural formula is as follows: Clopidogrel bisulfate is a white to off-white powder. It is practically insoluble in . CENTER FOR DRUG EVALUATION AND RESEARCH. Approval Package for: APPLICATION NUMBER: Orig1s Trade Name: PLAVIX Generic Name: clopidogrel bisulfate Sponsor: Sanofi Aventis Approval Date: March 12, Indication: Plavix is a P2Y12 platelet inhibitor indicated for: • Acute coronary syndrome. Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Its effect starts about two hours after intake and lasts for five days.

Retrieved 14 March Green Tea: Moderate Green tea has demonstrated antiplatelet and fibrinolytic actions in animals. If go here with platelet inhibitors is necessary, monitor platelet counts more frequently for evidence of thrombocytopenia. Archived from the original on 15 March Tell your doctor if you have ever had: an ulcer in your stomach or intestines; or a bleeding disorder or blood clotting disorder. Guaifenesin; Hydrocodone: Moderate Coadministration of opioid agonists, such as hydrocodone, delay and reduce the absorption of clopidogrel resulting in reduced exposure to active metabolites and diminished inhibition of platelet aggregation.

Garlic produces clinically significant antiplatelet effects, and a risk for bleeding may occur if platelet inhibitors are given in combination with garlic. Clopidogrel increases your risk of bleeding, which can be severe or life-threatening. Ketoconazole: Moderate Monitor for reduced clopidogrel efficacy during concomitant use of ketoconazole. Tucatinib: Major Avoid coadministration of tucatinib and clopidogrel due to the risk of increased tucatinib exposure which may increase the risk of adverse reactions.

what is the generic name for clopidogrel bisulfate

Medical Disclaimer See more A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Ticagrelor: Moderate Because clopidogrel and ticagrelor inhibit platelet aggregation, a potential additive risk for bleeding exists if the drugs zocor crestor given in combination. Geneva: World What is the generic name for clopidogrel bisulfate Organization. Experience is limited in patients with severe and moderate renal impairment; specific guidelines for dosage adjustments in renal impairment are not available. In clinical trials, bleeding rates with concomitant use of aspirin and clopidogrel vs.

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Oxcarbazepine is an inhibitor of CYP2C Dexlansoprazole, lansoprazole, and pantoprazole have less effect on antiplatelet activity. List of brand names. Nevertheless, the safety of this combination has not been established and concomitant administration of clopidogrel with heparin should be undertaken with caution. In vitro, luliconazole is a CYP2C19 inhibitor and small systemic concentrations may be noted what is the generic name for clopidogrel bisulfate topical application, particularly when applied to patients with moderate to severe tinea cruris. Reviewed: June 23, Drug Metab. Luliconazole: Minor What is the generic name for clopidogrel bisulfate for reduced clopidogrel efficacy during concomitant use of luliconazole. Moderate Coadministration of opioid agonists, such as oxycodone, delay and reduce the absorption of clopidogrel resulting in reduced exposure to active metabolites and diminished inhibition of platelet aggregation.

Drotrecogin Alfa: Major Treatment with drotrecogin can what lipitor drug replace should be carefully considered in patients who are receiving or have received any platelet inhibitors within 7 days. Codeine; Phenylephrine; Promethazine: Moderate Coadministration of opioid agonists, such as codeine, delay and reduce the absorption of clopidogrel resulting in reduced exposure to active metabolites and diminished inhibition of platelet aggregation.

what is the generic name for clopidogrel bisulfate

In children with Kawasaki disease who have severe coronary involvement, clopidogrel is recommended in combination with aspirin. Fedratinib: Moderate Monitor for reduced clopidogrel efficacy during concomitant use of fedratinib.

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ASPIRIN, CLOPIDOGREL \u0026 DOACs - THE TERRIBLE TRIO

Improbable: What is the generic name for clopidogrel bisulfate

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Rhe Moderate Carefully monitor patients for signs https://digitales.com.au/blog/wp-content/review/cholesterol/do-side-effects-happen-straight-away.php symptoms of bleeding during coadministration of escitalopram and clopidogrel. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. During clinical trials, the incidence of major bleeding increased with increasing age; the incidence of bleeding was higher in patients treated with combination clopidogrel and aspirin.

Theoretically, the risk of bleeding may be increased.

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What is the generic name for clopidogrel bisulfate - there

Betrixaban: Major Monitor patients closely and promptly evaluate any signs or symptoms of bleeding if betrixaban and platelet inhibitors are used concomitantly.

Luliconazole: Minor Monitor for reduced clopidogrel efficacy during concomitant use of luliconazole. Clopidogrel may also be used for purposes not listed in this medication guide.

what is the generic name for clopidogrel bisulfate

Escitalopram: Moderate Carefully monitor patients for signs and symptoms of bleeding during coadministration of escitalopram and clopidogrel. Clopidogrel is inactive in vitro and requires hepatic activation to exert its antiplatelet effect. Thrombolytic Agents: Major Concomitant administration of platelet inhibitors and thrombolytic agents could theoretically result in an increased risk of bleeding due to additive pharmacodynamic effects, and combinations of these agents should be approached with caution.

Clopidogrel keeps your vs reviews crestor zocor from coagulating clotting and can make it easier for you to bleed, even from a minor injury. Alfentanil: Moderate Coadministration of opioid agonists, such as alfentanil, delay and reduce the absorption of clopidogrel resulting in reduced exposure to active metabolites and teh inhibition of platelet aggregation. Plavix Clopidogrel. In clinical trials in patients undergoing PTCA, patients receiving bivalirudin with heparin, warfarin, or thrombolytics had increased risks of major bleeding events compared to those receiving bivalirudin alone. Clopidogrel should be used cautiously in patients with thrombocytopenia following the administration of myelosuppressive antineoplastic agents or other drugs that cause significant thrombocytopenia due to the genfric risk of bleeding.

Archived from the what is the generic name for clopidogrel bisulfate on 29 December

What generuc the generic name for clopidogrel bisulfate - doubt

Tucatinib: Major Avoid coadministration of tucatinib and clopidogrel due to the risk of increased tucatinib exposure which may increase the risk of adverse reactions. Geneva: World Health Organization. January The active metabolite of clopidogrel also inhibits platelet aggregation induced by agonists other than ADP by click the amplification of platelet activation by click at this page ADP; the active metabolite does not inhibit phosphodiesterase. If use together is necessary, monitor for bleeding and apalutamide-related toxicity; consider dose reduction based on tolerability in patients experiencing grade 3 or higher adverse reactions or toxicities.

Naproxen; Esomeprazole: Major Avoid concomitant use of clopidogrel and esomeprazole as it significantly reduces the antiplatelet activity of clopidogrel. Telmisartan; Hydrochlorothiazide, HCTZ: Major Telmisartan may reduce the antiplatelet activity of clopidogrel by inhibiting clopidogrel's metabolism to its active metabolite.

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Moderate Because dipyridamole is a platelet read article, there is a potential additive risk for bleeding if dipyridamole is given in combination with other agents that affect hemostasis such as ADP receptor antagonists including clopidogrel, prasugrel, ticagrelor, or ticlopidine. The efficacy and safety of administering injectable collagenase to a patient taking a platelet inhibitor within 7 days before the source are unknown. Required field. Milnacipran: Moderate Carefully monitor patients for signs and symptoms of bleeding during coadministration of milnacipran and platelet inhibitors. Consensus-based article source guidelines also recommend the use of clopidogrel rather than aspirin ASA for antiplatelet therapy in people with a history of gastric ulceration, as inhibition of the synthesis of prostaglandins by ASA can exacerbate this condition.

Codeine: Moderate Coadministration of learn more here agonists, what is the generic name for clopidogrel bisulfate as codeine, delay and reduce the what is the generic name for clopidogrel bisulfate of clopidogrel resulting in reduced exposure to active metabolites and diminished inhibition of platelet aggregation. Namespaces Article Talk. Due to the thrombocytopenic effects of vorinostat, an additive risk of bleeding may occur in patients taking platelet inhibitors.

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