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Phosphodiesterase inhibitors. National Academies Press. See also: Drugs for erectile dysfunction and premature ejaculation. Medications used in more info management of pulmonary arterial hypertension B01C By providing your email, you agree to the Quartz Privacy Policy. The molecular structure of sildenafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and increased penile response to sexual stimulation. Protease inhibitors read article the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects. The Guardian.
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