Survival rate of lupus Video
Systemic Lupus Erythematosus (SLE) in Children – Pediatrics - Lecturio survival rate of lupus
Each one-unit increase on a disease activity score during the first year after enrollment into a systemic lupus erythematosus SLE cohort was associated with a significant increased risk for death and organ damage during subsequent follow-up, researchers reported. However, treatment with hydroxychloroquine significantly reduced the likelihood of damage.
luups Survival rates have risen dramatically in recent decades, but irreversible organ damage remains an important concern, with patients who have organ damage being likely to develop more damage, thus lessening their likelihood of survival. Therefore, to explore the current pattern of damage accrual among patients with SLE in a racially diverse study population, Petri's group analyzed data from their cohort, including 1, patients enrolled from to Patients with at least 2 years of follow-up were included in the analysis.
Disease activity was assessed at each quarterly clinic visit, along with data on medication use, comorbidities, and damage to the renal, cardiovascular, peripheral vascular, pulmonary, surviva, and musculoskeletal systems. Median age at cohort enrollment was Medication use included oral prednisone in There were no differences in the risk of damage when the analysis was stratified by race.
Background
The findings of increased cardiovascular damage with NSAID and antihypertensive use "may suggest that the known cardiovascular risk of NSAIDs in the general population is also applicable to patients with SLE and highlights the importance of assessing cardiovascular risk in this patient population," Petri and colleagues wrote. The study confirmed that even minor fluctuations in disease activity in patients with mild-to-moderate disease "underscore the need for active measures to manage SLE disease activity over time," the authors concluded. Petri reported being a paid consultant to GSK; three of the other four co-authors reported being paid employees survival rate of lupus the company with stock options and conducting the study as part of their employment using GSK resources; the other co-author reported being a paid contractor for GSK.]
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